Manipulation of lymphoid microenvironments in nonhuman primates by an inhibitor of the lymphotoxin pathway
J. Clin. Invest. Jennifer L. Gommerman, et al. 110:1359 doi:10.1172/JCI15975 [
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Figure 1FDC networks in the spleen are eliminated in animals treated with LTβR-Ig. Representative spleens from untreated (
a and
b), treated (8 mg/kg LTβR-Ig) (
c and
d), and recovery animals (8 mg/kg treatment followed by 3-month recovery) (
e and
f) were stained with anti-CD35 Ab’s and developed with AP-red. Spleens were counterstained with Giemsa and photographed at ×25 (
a,
c,
e) or ×100 (
b,
d,
f).
