Spontaneous circulation of myeloid-lymphoid–initiating cells and SCID-repopulating cells in sickle cell crisis
J. Clin. Invest. Christopher E.D. Lamming, et al. 111:811 doi:10.1172/JCI15956 [Go to this article.]

Figure 2
Significantly more CD34⁺CD38^–Lin^– cells are present per 10⁵ PBMCs from AC-SCD patients compared with NL donors and SS-SCD patients. Mononuclear cells were selected from blood from normal donors, SS-SCD patients, and AC-SCD patients. Following enrichment for CD34⁺ cells and Lin^– cells, CD34⁺CD38^–Lin^– cells were selected by FACS. Significantly more CD34⁺CD38^–Lin^– cells were detected among mononuclear cells from AC-SCD blood compared with SS-SCD and NL-donor blood. Differences between the groups were evaluated by Student’s t test.