Jci_page_head_homepage_01 Jci_page_head_homepage_02
Cord Brakebusch, Daniel Bouvard, Fabio Stanchi, Takao Sakai, Reinhard Fässler
Published in Volume 109, Issue 8
J Clin Invest. 2002; 109(8):999–1006 doi:10.1172/JCI15468
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Figure 3

Integrin control of cell survival. Integrin activation of Akt via PI3-K or ILK plays an important role in the antiapoptotic effect of integrin-mediated adhesion. Activation of Erk and JNK likewise contributes to increased cell survival.