Hypothalamic Y2 receptors regulate bone formation
J. Clin. Invest. Paul A. Baldock, et al. 109:915 doi:10.1172/JCI14588 [Go to this article.]

Figure 6
Effect of adult induced hypothalamus-specific Y2 receptor deletion on trabecular bone of the distal femoral metaphysis. Trabecular bone volume (a), trabecular number (b), and trabecular thickness (c) in male Y2^+/+ Cre-adeno-virus–injected or Y2^lox/lox GFP-adenovirus–injected control mice (white bars) compared with Y2^lox/lox Cre-adenovirus–injected mice (KO, black bars) at 15–17 weeks of age. Values are mean ± SD of five to seven mice per group. *P < 0.01, **P < 0.001 versus controls.