Hypothalamic Y2 receptors regulate bone formation
J. Clin. Invest. Paul A. Baldock, et al. 109:915 doi:10.1172/JCI14588 [
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Figure 3Effect of germline Y2 receptor deletion on trabecular bone of the distal femoral metaphysis. Trabecular bone volume (
a), trabecular number (
b), and trabecular thickness (
c) of femora from male wild-type mice (WT, white bars) compared with heterozygous
Y2+/– (het, gray bars) and homozygous
Y2–/– mice (KO, black bars) at 15–17 weeks of age. Values are mean ± SD of five to eight mice per group. *
P < 0.05, **
P < 0.01 versus wild-type mice.
