Targeted disruption of the Chop gene delays endoplasmic reticulum stress–mediated diabetes
J. Clin. Invest. Seiichi Oyadomari, et al. 109:525 doi:10.1172/JCI14550 [Go to this article.]

Figure 6
Development of diabetes in male Ins2^WT/C96YChop^+/+, Ins2^WT/C96YChop^+/–, and Ins2^WT/C96YChop^–/– mice. Mice were provided food ad libitum, and blood glucose was measured between 9:00 a.m. and 10:00 a.m. Ins2^WT/C96YChop^+/+ mice (filled squares), Ins2^WT/C96YChop^+/– mice (filled circles), and Ins2^WT/C96YChop^–/– mice (open circles) are represented. Data are shown as mean ± SD (n = 7).