Targeted disruption of the Chop gene delays endoplasmic reticulum stress–mediated diabetes
J. Clin. Invest. Seiichi Oyadomari, et al. 109:525 doi:10.1172/JCI14550 [Go to this article.]

Figure 1
Development of diabetes in Akita mice. Mice were provided food ad libitum, and blood glucose was measured between 9:00 a.m. and 10:00 a.m. at indicated age. (a) Male. (b) Female. Wild-type Ins2^WT/WT mice (open circles), heterozygous Ins2^WT/C96Y mice (filled circles), and homozygous Ins2^C96Y/C96Y mice (filled squares) are represented. Data are shown as mean ± SD (n = 10).