Choreoathetosis, hypothyroidism, and pulmonary alterations due to human NKX2-1 haploinsufficiency
J. Clin. Invest. Heiko Krude, et al. 109:475 doi:10.1172/JCI14341 [
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Figure 4Expression of the NKX2-1 protein in human and rat adult tissues. (
a) Human basal ganglia. The inset shows no nuclear staining of the NKX2-1 Ab. Nuclear staining is visible in human lung (
b) and human thyroid (
c). In the rat brain (
d) staining is negative in the pallidum (as shown in the inset) on a cellular level but positive in the lung (
e) and the hypothalamus (
f). pu, putamen; pa-l, lateral pallidum; pa-m, medial pallidum; ic, internal capsle.