Role of sarcolemmal KATP channels in cardioprotection against ischemia/reperfusion injury in mice
J. Clin. Invest. Masashi Suzuki, et al. 109:509 doi:10.1172/JCI14270 [
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Figure 5Changes in LVP during ischemia and reperfusion. Representative LVP changes in untreated WT (WT-CON,
a), 5-HD–treated WT (WT-5HD,
b), HMR1098-treated WT (WT-HMR,
c), untreated KO (KO-CON,
d), 5-HD–treated KO (KO-5HD,
e), and HMR1098-treated KO hearts (KO-HMR,
f) are shown. The traces from WT-CON and KO-CON hearts are partly expanded in the insets. Arrows with full line and those with dashed line show the time points of cessation of contraction and onsets of contracture, respectively. Note that KO hearts continued to contract for a longer time than the WT hearts did during ischemia.
