Role of sarcolemmal KATP channels in cardioprotection against ischemia/reperfusion injury in mice
J. Clin. Invest. Masashi Suzuki, et al. 109:509 doi:10.1172/JCI14270 [
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Figure 4Mitochondrial K
ATP channel activities assessed by changes in flavoprotein fluorescence. The effects of 100 μM diazoxide on flavoprotein fluorescence of representative cells isolated from (
a) WT and (
b) KO mice. Bars indicate periods of diazoxide application. (
c) Summarized data for percentage of flavoprotein oxidation. Despite the absence of surface
IK,ATP in KO cells, they displayed response to diazoxide similar to that of WT.