Role of sarcolemmal KATP channels in cardioprotection against ischemia/reperfusion injury in mice
J. Clin. Invest. Masashi Suzuki, et al. 109:509 doi:10.1172/JCI14270 [
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Figure 1In vivo myocardial infarction studies. (
a–
d) Representative photographs of myocardial slices of WT-CON mice (
a), WT-IPC mice (
b), KO-CON mice (
c), and KO-IPC mice (
d) are shown. A schema of each photograph is indicated below; infarct area is expressed as gray, viable myocardium in AAR as red, and nonischemic area as blue. Scale bar = 2 mm. (
e) Myocardial infarct size expressed as percentage of AAR for WT-CON (
n = 6), WT-IPC (
n = 6), KO-CON (
n = 6), and KO-IPC (
n = 6). There were no significant differences in the infarct size between WT-CON and KO-CON or between KO-CON and KO-IPC. Values are expressed as mean ± SE. NS, not significant. *
P < 0.01 versus WT-CON.