Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13–induced inflammation and remodeling
J. Clin. Invest. Sophie Lanone, et al. 110:463 doi:10.1172/JCI14136 [Go to this article.]

Figure 1
Effect of MMP-9 and MMP-12 deficiency on IL-3–induced alterations in lung size. CC10-rtTA-IL-13 transgene^– and transgene⁺ mice with wild-type and null MMP-9 (top) or MMP-12 (bottom) loci were generated and placed on dox water at 1 month of age. They were maintained on this regimen for an additional month, at which time their lungs were removed, fixed to pressure, and photographed.