CD4⁺ T cells specific to a glomerular basement membrane antigen mediate glomerulonephritis
J. Clin. Invest. Jean Wu, et al. 109:517 doi:10.1172/JCI13876 [Go to this article.]

Figure 8
Tracing CFDA-SE–labeled T cells in kidney cortex by fluorescent microscopy. (a and b) rCol4α3NC1-specific T cells or CFA T cells were transferred into naive recipients. The labeled cells were counted in serial frozen sections of the kidney cortex 24 hours later, and labeled cell density was calculated (a). Elongated cells are expressed as a percentage of all labeled cells (b). (c) Fluorescent microscopy illustrates an elongated rCol4α3NC1-specific cell (green) in the Bowman’s capsule. GBM is stained red by PE-labeled SR-13. The tubules (T) with background are visible. Inset: high power of two elongated, labeled T cells.