CD4+ T cells specific to a glomerular basement membrane antigen mediate glomerulonephritis
J. Clin. Invest. Jean Wu, et al. 109:517 doi:10.1172/JCI13876 [
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Figure 4Proteinuria and albuminuria development in the rCol4α3NC1-specific T cell recipients. (
a) Urine samples were collected as indicated (
x axis) in 11 T cell recipients, and proteinuria was measured (
y axis). Filled symbols, rats with severe GN; open symbols, modest GN; dashed lines, normal kidney. (
b) Urine samples from a representative T cell recipient (T cell) with severe GN and a rat immunized with rCol4α3NC1 (rCol) were analyzed by SDS-PAGE. Arrows at right indicate serum albumin.