CD4+ T cells specific to a glomerular basement membrane antigen mediate glomerulonephritis
J. Clin. Invest. Jean Wu, et al. 109:517 doi:10.1172/JCI13876 [
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Figure 2Cellular composition of rCol4α3NC1-specific T cell lines. (
a) Flow cytometry analysis of whole lymphocytes from rCol4α3NC1-immunized rats (top panel) and a T cell line (bottom panel). (
b) Rat IgG concentration in the supernatants of two Col4α3NC1 T cell lines (open circles and squares) and one control CFA T cell line (filled circles) collected after each stimulation (
x axis). Ab activities to rCol4α3NC1 in the supernatants from a Col4α3NC1 T cell line, determined by Western blot analysis, are shown (inset).