Muscle-specific inactivation of the IGF-I receptor induces compensatory hyperplasia in skeletal muscle
J. Clin. Invest. Ana M. Fernández, et al. 109:347 doi:10.1172/JCI13503 [Go to this article.]

Figure 6
Differential expression of p21 and Twist in MKR mice. Hindlimb muscles were removed from WT and MKR mice at the ages of 0–3 weeks, 5 weeks, and 8 weeks, and subjected to Northern or Western blot analysis, as indicated below. (a) Northern blot analysis of Twist levels in MKR and WT mice (upper panel). 18S RNA levels were similar in all the groups (lower panel). (b) Western blot analysis of Twist (upper panel) and β-actin (lower panel) immunoreactivity levels in MKR and WT mice. (c) Western blot analysis of p21 (upper panel) and β-actin (lower panel) immunoreactivity levels in MKR and WT mice. Data are expressed as the mean ± SEM of three independent experiments, using five animals in each group.