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SPARC, a matricellular protein that functions in cellular differentiation and tissue response to injury
Amy D. Bradshaw, E. Helene Sage
Published in Volume 107, Issue 9
J Clin Invest. 2001; 107(9):1049–1054 doi:10.1172/JCI12939
This article Copyright © 2001, The American Society for Clinical Investigation
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Figure 2

SPARC-null lens epithelial cells display changes in cell shape and alignment in comparison with wild-type cells. Sections from similar areas of wild-type and SPARC-null lens were stained with hematoxylin and eosin. Cortical fibers from a 3-month-old wild-type lens (a) are regular and precisely aligned, whereas those from a SPARC-null lens (b) are irregular in shape and alignment. Magnification, ×220.

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