SPARC, a matricellular protein that functions in cellular differentiation and tissue response to injury
J. Clin. Invest. Amy D. Bradshaw, et al. 107:1049 doi:10.1172/JCI12939 [Go to this article.]

Figure 2
SPARC-null lens epithelial cells display changes in cell shape and alignment in comparison with wild-type cells. Sections from similar areas of wild-type and SPARC-null lens were stained with hematoxylin and eosin. Cortical fibers from a 3-month-old wild-type lens (a) are regular and precisely aligned, whereas those from a SPARC-null lens (b) are irregular in shape and alignment. Magnification, ×220.