Extrarenal effects on the pathogenesis and relapse of idiopathic nephrotic syndrome in Buffalo/Mna rats
J. Clin. Invest. Ludmilla Le Berre, et al. 109:491 doi:10.1172/JCI12858 [
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Figure 7(
a) Proteinuria following renal transplantation of Buffalo/Mna kidneys placed into nonproteinuric binephrectomized LEW.1W recipients treated with DST before transplantation to induce tolerance (two individuals). Comparison is made with proteinuria of age-matched, unmodified, or uninephrectomized Buffalo/Mna rats (
n = 5). Proteinuria is expressed as the ratio of the urinary protein to urinary creatinine concentration. Error bars indicate standard deviation. (
b) Light microscope examination of Buffalo/Mna kidneys grafted into nonproteinuric LEW.1W rats (PAS staining, ×400) showing a subnormal histology.