JCI - α4-integrin-VCAM-1 binding mediates G protein–independent capture of encephalitogenic T cell blasts to CNS white matter microvessels

α4-integrin-VCAM-1 binding mediates G protein–independent capture of encephalitogenic T cell blasts to CNS white matter microvessels
J. Clin. Invest. 108:4 doi:10.1172/JCI12440 [Go to this article.]

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Figure 1

Spinal window preparation for direct intravital microscopic assessment of white matter microcirculation. Stereomicroscopic (a) and intravital fluorescence microscopic (b) view of spinal window preparation exposing the dorsal spinal cord. Bar, 500 μm. High-magnification intravital fluorescence microscopy of spinal microvasculature depicting white matter capillary network (arrows) (c) and white matter postcapillary venules draining into the central dorsal vein (d). Bar, 100 μm.