7-Dehydrocholesterol–dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome
J. Clin. Invest. Barbara U. Fitzky, et al. 108:905 doi:10.1172/JCI12103 [Go to this article.]

Figure 3
Activity of Dhcr7 (picomoles per milligram of protein per minute) as measured by the conversion of [³H]-7DHC to cholesterol in liver homogenates from newborn Dhcr7^–/–, Dhcr7+/–, and Dhcr7+/+ mice.