7-Dehydrocholesterol–dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome
J. Clin. Invest. Barbara U. Fitzky, et al. 108:905 doi:10.1172/JCI12103 [
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Figure 2Genotyping of
Dhcr7–/–,
Dhcr7+/–, and
Dhcr7+/+ newborn mice from heterozygous matings by PCR using primers specific for mouse exons 7 and 8 as described in Methods and in Figure
1a.