Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB
J. Clin. Invest. Albert S. Baldwin, et al. 107:241 doi:10.1172/JCI11991 [Go to this article.]

Figure 1
Induction of NF-κB by TNF or other stimuli leads to the transcriptional activation of genes that suppress apoptosis. The proteins encoded by the genes function at different levels in the caspase cascade to block apoptosis.