Increased diameter of hair shafts in 12-week-old VEGF transgenic mice (VEGF TG) during late anagen, as compared with wild-type (WT) littermates. (a) Light microscopy of unstained plucked awl hair; scale bar = 30 μm. (b) Quantitative analysis of hair shafts, measured at the level of their greatest width, revealed a significantly increased hair diameter in VEGF transgenic mice. Data are expressed as means ± SD (n = 50 for each genotype). ^AP < 0.001, two-sided unpaired Student’s t test.