Jci_page_head_homepage_01 Jci_page_head_homepage_02
Article tools
  • View PDF
  • Cite this article
  • E-mail this article
  • Share this article
  • Send a letter
  • Information on reuse
  • Standard abbreviations
Author information
Need help?

Articles

Frequency dependence of compliance as a test for obstruction in the small airways

Ann J. Woolcock, N. J. Vincent and Peter T. Macklem

Respiratory Division, Department of Medicine, Royal Victoria Hospital, McGill University, Montreal, Canada

Published June 1969

We selected five bronchitics and four asthmatics in remission, whose routine lung function tests were not significantly abnormal. Dynamic compliance was measured at different respiratory frequencies and the results compared with those obtained from a normal control group. In all patients compliance was frequency dependent and remained so after the administration of bronchodilator aerosols. Compliance was frequency dependent in only one normal subject, and this was completely reversed by bronchodilators. Because the elastic properties of the patients' lungs were normal, and because pulmonary resistance was normal or only minimally increased, we interpret these results as indicating obstruction in peripheral airways.

Browse pages

Click on an image below to see the page. View PDF of the complete article