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PYRIMIDINE METABOLISM IN MAN. V. THE MEASUREMENT IN VIVO OF THE BIOCHEMICAL EFFECT OF ANTINEOPLASTIC AGENTS IN ANIMAL AND HUMAN SUBJECTS*

Mitchell T. Rabkin, Elizabeth W. Frederick, Myron Lotz and Lloyd H. Smith, Jr.

Department of Medicine, Harvard Medical School, Boston, Mass.Department of Medicine, Massachusetts General Hospital, Boston, Mass.

Postdoctoral Research Fellow, National Institute of Arthritis and Metabolic Diseases.

* This work was supported by Grant A-4080, National Institutes of Health, United States Public Health Service. Published in part in abstract form (J. clin. Invest. 1961, 40, 1073).

Published April 1962

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