Published in Volume 39, Issue 12 (December 1960)
J Clin Invest. 1960;39(12):1914–1926. doi:10.1172/JCI104216.
Copyright © 1960, The American Society for Clinical Investigation.

Articles

TRANSCORTIN: A CORTICOSTEROID-BINDING PROTEIN OF PLASMA. III. THE EFFECTS OF VARIOUS STEROIDS *†

Avery A. Sandberg, W. Roy Slaunwhite, Jr. and Anne C. Carter

^{Roswell Park Memorial Institute, Buffalo, N. Y.}^{Department of Medicine, State University of New York, N. Y.}^{College of Medicine at New York City, N. Y.}

^* This investigation was supported in part by grants (A-1240-C3) from the National Institute of Arthritis and Metabolic Diseases and from the National Cancer Institute (CY-3601), Bethesda, Md.

^† The following abbreviations have been employed—cortisol: 11β,17α,21-trihydroxy-4-pregnene-3,20-dione; dihydrocortisol (H2F): 11β,17α,21-trihydroxy-pregnane-3,20-dione; tetrahydrocortisol (H4F): 3α,11β,17α,21-tetrahydroxy-pregnane-20-one; 9α-fluorocortisol: 9α-fluoro-11β,17α,21-trihydroxy-4-pregnene-3,20-dione; cortisone: 17α,21-dihydroxy-4-pregnene-3,11,20-trione; dihydrocortisone (H2E): 17α,21-dihydroxy-pregnane-3,11,20-trione: tetrahydrocortisone (H4E): 3α,17α,21-trihydroxy-pregnane-11,20-dione; corticosterone: 11β,21-dihydroxy-4-pregnene-3,20-dione; aldosterone: 11β,21-dihydroxy-18-aldo-4-pregnene-3,20-dione: Compound S (11-deoxycortisol): 17α,21-dihydroxy-4-pregnene-3,20-dione; 6α-methylprednisolone: 6α-methyl-11β,17α-21-trihydroxy-1,4-pregnadiene-3,20-dione; 17α-hydroxyprogesterone (17-OHPg): 17α-hydroxy-4-pregnene-3,20-dione; Δ4-androstenedione: 4-androstene-3,17-dione; 17α-methyl-19-nortestosterone: 17α-methyl-17β-hydroxy-4-estrene-3-one; testosterone propionate: 17β-propionoxy-4-androsten-3-one; 2α-methyl-dihydrotestosterone propionate: 2α-methyl-17β-propionoxy-androstan-3-one; estriol: 1,3,5 (10)-estratriene-3, 16α, 17β-triol; 16α-estradiol dipropionate: 1,3,5 (10)-estratriene-3,16α-dipropionate; Estinyl: 17α-ethinyl-3,17β-dihydroxy-1,3,5 (10)-estratriene; stilbestrol: 3,4-bis (p-hydroxyphenyl)-3-hexene; Premarin: conjugated equine estrogens, containing approximately 90 per cent estrone sulfate; ACTH: adrenocorticotropin.

Published December 1960