Treatment of murine lupus with cDNA encoding IFN-γR/Fc
J. Clin. Invest. Brian R. Lawson, et al. 106:207 doi:10.1172/JCI10167 [Go to this article.]

Figure 4
Long-term in vivo BrdU incorporation (9 days in drinking water) in T-cell subsets of mice treated late in the disease with either the blank plasmid (left panels) or the IFN-R/Fc cDNA plasmid (right panels) coupled with electroporation. Assessments were made 7 months after initiation of treatment. Cells were first stained with the indicated surface markers, fixed, stained with anti-BrdU, and analyzed by FACS. Profiles are representative of one mouse, and mean ± SEM of BrdU^hi (cycling) cells are derived from four mice per group.