Evidence for angiotensin II type 2 receptor–mediated cardiac myocyte enlargement during in vivo pressure overload
J. Clin. Invest. Takaaki Senbonmatsu, et al. 106:R25 doi:10.1172/JCI10037 [Go to this article.]

Figure 2
Pathological analysis in the Agtr2^–/Y and wild-type mouse heart. (a) Cross section of midportion of left ventricle in aortic-banded Agtr2^–/Y and wild-type mice. (b) Left ventricular CSA in aortic-banded Agtr2^–/Y and wild-type mice, and in Agtr2^–/Y and wild-type mice before banding. ^AP < 0.05. (c and d) Collagen type I in aortic-banded Agtr2^–/Y and wild-type mouse hearts and in sham-operated Agtr2^–/Y and wild-type mouse hearts. Lane 1: aortic-banded Agtr2^–/Y; lane 2: aortic-banded wild-type; lane 3: sham-operated Agtr2^–/Y; lane 4: sham-operated wild-type mouse hearts. Data are representative of three independent experiments with nearly identical results.