Evidence for angiotensin II type 2 receptor–mediated cardiac myocyte enlargement during in vivo pressure overload
J. Clin. Invest. Takaaki Senbonmatsu, et al. 106:R25 doi:10.1172/JCI10037 [
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Figure 1(
a) Systolic blood pressure in
Agtr2–/Y and wild-type mice. Filled circles: aortic-banded
Agtr2–/Y mice; filled squares: aortic-banded wild-type mice; open circles: sham-operated
Agtr2–/Y mice; open squares: sham-operated wild-type mice.
AP < 0.05. (
b) IVS and LVPW in aortic-banded
Agtr2–/Y and wild-type mice. Filled circles: IVS in aortic-banded
Agtr2–/Y mice; filled squares: IVS in aortic-banded wild-type mice; open circles: LVPW in aortic-banded
Agtr2–/Y mice; open squares: LVPW in aortic-banded wild-type mice.
AP < 0.05. (
c) LVM of
Agtr2–/Y and wild-type mice. Filled circles: aortic-banded
Agtr2–/Y mice; open circles: sham-operated
Agtr2–/Y mice; filled squares: aortic-banded wild-type mice; open squares: sham-operated wild-type mice.
AP < 0.05.